Abstract Background Multiple myeloma (MM) remains an incurable malignancy, despite the advent of therapies such as proteosome inhibitors (PIs) that disrupt protein homeostasis and induce ER stress.We have pursued inhibition of geranylgeranyl diphosphate synthase (GGDPS) as a novel mechanism by which to target protein homeostasis in MM cells.GGDPS i
This paper studies the performance analysis of wireless energy harvesting (EH) cluster-based multi-hop networks, where all communication nodes harvest energy from the radiated signals transmitted by multiple power beacons (PBs) to support the information transmission.To this end, we propose three relay selection schemes.The first scheme tries to se
Introduction: Aspirated foreign bodies continue to present challenges to otorhinolaryngologists.Removal of impacted airway foreign bodies via conventional methods can at times pose difficulty.This may berelated to the location and type of foreign body, experience of the surgeon and anesthetist, and the availability of appropriate instruments.In adu
This study investigates how societal preferences impact policy choices in the trade-off between exchange rate stability and monetary policy autonomy.Building on the theoretical approach of economic pluralism, it is argued that the size us polo assn mens sweaters and strength of different economic actors are the central determinants for monetary pol